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MMB-2201 (also known as 5F-MMB-PICA, 5F-AMB-PICA, and I-AMB) is a potent indole-3-carboxamide based synthetic cannabinoid, which has been sold as a designer drug and as an active ingredient in synthetic cannabis blends. It was first reported in Russia and Belarus in January 2014, but has since been sold in a number of other countries. In the United States, MMB-2201 was identified in Drug Enforcement Administration drug seizures for the first time in 2018.

MMB-2201 is the indole core analogue of 5F-AMB. Synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a N-1-methoxycarbonyl group with attached isopropyl or tert-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds not for human consumption. Only for research purposes.

It was first identified in March 2012, in Japan, in a herbal mixture sold. In Europe it is listed since September 2012 as AKB-48-F. In the European Union, 19 member countries out of 28 have reported its identification, mainly through seizures of people. In Sweden the product is implicated with several other products in two deaths, and implicated alone in an intoxication.

The product was identified in France via a SINTES collection for the first time in 2013, in the form of a powder purchased by a user on the Internet.

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What is that ?

Appearance, what does it look like?

5F-AKB48 Powder

crystalline white powder

Other names and nicknames

Synonym: 5F-AKB48, N-(adamantan-1-yl)-1-(4-fluorobutyl)-1H-indazole-3-carboxamide, APINACA 5-fluoropentyl analog, 5F-APINACA

The price

powder: €14 per gram

e-liquid: €25 for a 4ml vial of Buddha Blue

Fusion point

54.9 °C

Consumption patterns

C-Liquid brand e-liquid containing 5F-AKB48

Like most other cannabinoids, 5F-AKB48 can be smoked in its pure powder form or incorporated into dried plant material and smoked with a pipe. 5F-AKB45 can also be mixed with propylene glycol (PG) and vaporized using an electronic cigarette. There are recipes on the internet [1] allowing it to be integrated into the PG, but websites also sell ready-made e-liquids such as Buddha Blue or C-liquid [2] . In fact, the e-cigarette does not vaporize the liquid, it produces an aerosol. There is therefore no need for the molecule to be vaporized to be inhaled, it is contained in the microdroplets of propylene glycol or glycerin which are deposited in the bronchi and alveoli.

In addition 5F-AKB48 can be consumed orally with the help of food containing high doses of fat, such as milk, cream, butter, peanut butter and olive oil. .

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" The most "safe" process would be to put a little powder along a rolled cigarette, to put the smallest possible quantity: 1 or 2 milligrams should be enough for the first time. You smoke gently: one or two puff then you can put the cigarette down to wait and see the effects. Start again, etc.

It is not recommended to redose for the first. (don't forget the day before to do an allergy test with 1 milligram if you can)

»

" So here it is, it's been almost two years that I consume 2~3 min cones daily (ed. of cannabis). For my current situation it has become uncomfortable financially speaking. Lover of new things, I ordered 1 g of 5F-AKB48 which I then transformed for vaping . So I've been vaping this thing for more than a month, of course besides I was still smoking my joints. Everything has changed since heads have fallen in my house, including those of my dealer. Hard, hard, but with the magic electronic cigarette its work/help (to see in the longer term). Of course it's not the same thing; stoned + short & + strong, , + energy .. »

-(Source, benox , Psychoactive )

Dosage

When smoked into a powder, the dosage is 2-5mg . Best is to spread 2-5mg in a joint, pull a latte and wait for the high to happen. Repeat several times.

You can also dose 5F-AKB48 in e-liquid to vape it using an electronic cigarette. The concentration of 10mg/ml seems to be correct.

" I confirm that the Recklinghausen recipe presented at the top of the discussion works wonderfully. I don't have enough hindsight or experience to judge possible or desirable concentrations. Anyway, I can only approve of the 10mg/ml concentration for the 5F AKB 48. No sore throat, correct hit, rather light effect as far as I'm concerned but sufficient with an eGo AIO e-cigarette "basic" and its original resistance at 0.6 Ohms. »

-(Source, Lolyve , Psychoactive )

The desired effects

The effects are stronger than the effects of the cannabis plant. On the other hand, the effects last less: from 30 minutes to 2 hours with the descent. They can be :

euphoria

relaxation

Feeling of joy and laughter

hot flush

hallucinations

" For my part 5F AKB 48 is a pretty bales canabinoid. Following the various advice on several forums I made myself a firecracker with a micro line making a little less the length of my sheet. I shot myself 4 bars while keeping the smoke well, I put the fart, I continued my activity of wedging skeuds. About 5 minutes later I felt the first effects, feeling of warmth in the face, ears that began to buzz. To my surprise it continued to rise, I found myself at a level where I had to drop the plates. My mind was confused, heartbeat quite pronounced, nothing insurmountable (like after a good crack socket).

I sat in my chair facing my speakers, letting myself be carried away by the sound, saying to myself...WOW, that sends this mess! I experienced it very well having already experienced intense highs. For me the maximum level was like under poppers (hot flash, tachycardia) coupled with a good drop of drops (concentration very difficult for colored vision)  . 

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Once I reached my cruising speed, I let myself be overwhelmed by the zik (acid / mental), I was in a state of fullness but still otaked. It was good to be for me for a good half hour, then went down slowly, my mouth was dry, drinking a little water went very well. In the end it's very nice, once you've tried it, these manageable, above all don't panic, it goes down pretty quickly. but I conceive that some have a flip, mounted and surprising plateau the first time, after we like it or not from the first experience. For my part I liked, however not to put in all hands. Please note there is little ganja effect except on the descent, rather physical and psychedelic effect .....    this is a really interesting product for those who like pole ..... 

»

" The effects last in myenne for me about 2 hours, because after 2 months we hold the prod better, we savor more, big desire to re-drop when we have raudé the thing. 35 mn of climbing, 45 mn of plateau, the rest of the time is the descent and we don't see past, positive side, the horrible plastic taste, the first time that I chek this noid I took 4 hours in the nose ! »

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" I had 1.33g of 5F-AKB48 (normally 1g but I had 0.33g more :p) Really not bad its looks like weed but less stone much more hight . Fairly low anxiety, disinhibiting and sedative in 'descent' or in large doses.

Paranoid probably more common than weed and quite violent bad potential (a friend had one the first evening with 5F-AKB48 but has already done it with weed. According to him, it's like weed bads only worse) .

It's a good cannabinoid in my opinion but has to do with the medium / long term effects.

Dosage level I do it at the tip of a knife but the hotspots in the joint are quite frequent I will try to infuse it in tobacco as soon as I am motivated

»

The risks of consumption

Inhaling any combustion product is harmful to the lungs, esophagus, mouth, or sinuses. This is only true when smoking 5F-AKB48, not when vaping it.

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5F-AKB48 is new for human consumption . There are no scientific studies on its short, medium and long term risks.

If you have a history of mental or physical health, 5F-AKB48 can amplify them.

The side effects

• hunger

• short term memory loss

• anxiety, panic attack

• paranoia

• confusion

• Dry mouth

• headache

• Increase in body temperature

• tachychardia

" The majority of bad Noids are due to the fact that the user is impressed by the rise and starts to worry, rather than having a real overdose...(source: my friends. lol) And even in a smoker accustomed to cannabinoids it can happen... (source:myself) (damn this bad!!!)

In the event of a split in the balls: You have to keep in mind that the effect of the rush is very short and that it will pass quickly . heartbeats, it will only make them go up. Lie down, breathe well and in 15 minutes it will already be much better...

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»

" It happened to me too dosed by idnatvèrtence while bugant on the TV while I prepare a Douille. From small cayou I thought it would go past but with this prod, you shouldn't overestimate it, the Ascent you have the impression that your 2 peripheral extremities of the brain are going to explode, it's starting to get confused in your head, everything becomes blurry, it doesn't stop rising more and more, your body is a little stimulated, your heart is low, sweaty palm, you are building up pressure , you think you see a small shadow moving on the side of your sight, but nothing, dizziness, accoufênne, nausea,and in the worst case when I was staring at kk thing the image remained etched in my head even as I saw small flashbizzar elsewhere like a juice and it's always at this moment that a small black hole passes 2 sec, it's generally kan you go from the climb to the plateau, and from the plateau to the descent, I noticed it as a kind of signal, tell me if it gives you the same symptom with the overdose of b48, or if it's me who's screwing up. »

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" Definitely my worst bad tonight with this product! Being almost naïve to cannabis, and having only an unsuitable balance, I took it while smoking, in a glass of thinner and in a yogurt last night, with friends. Dosed with the tip of a spoon, in other words, we were far from the regulatory 3-4 mg. Add to that a pinch of methoxphenidine and BK-2CB, as well as a little alcohol and you have a molotov cocktail? 

However, it would be dishonest to blame them, as these last substances had little impact on my reactions. Because, and I had felt it from the first puffs, the 5F-AKB48 has nothing to envy to hard drugs in terms of its climbs which are, as said before, imprinted with psychedelia. By itself, and well after the rest, it will create this famous feeling of unreality, coupled with the moment of sleep by the sensation of leaving, of leaving this world . A nice paranoid? Possible. I still felt like I was close to respiratory depression.

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»

" In total panic, I continue like an idiot to pull slats on it as if nothing had happened, and after 2 minutes the mental fracture begins. Peripheral vision totally blurred or even hallucinogenic, paranoia, totally confused reasoning . At the limit of a nervous breakdown (the tachycardia that the 5f-akb-48 causes me plus the stress is just horrible), I was relieved when the police (s) told me to circulate because the place was dangerous »

-(Source, Haribo1202 , Psychoactive )

Tolerance, habituation, dependence

Use of 5F-AKB48 may lead to the development of tolerance, the onset of dependence, and withdrawal symptoms upon discontinuation.

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" Lover of new things, I ordered 1 g of 5F-AKB48 which I then transformed to vape it. So I've been vaping this thing for over a month... Of course it's not the same as cannabis; stoned + short & + strong, , + energy .. On the other hand I have the impression of developing a dirty tolerance . »

-(Source, benox , Psychoactive )

" To return to the subject yes a tolerance settles down including in eliquid but should not exceed 6 taff (it also depends on the dosage I speak for a solution at 30mg / ml), this one goes down very quickly in about a week so be careful to overdose at the time of recovery ! »

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" Oh yes, I also wanted to say: pay attention to the recovery after a long period of cessation or after having taken a type of noid then having stopped for a few weeks and having switched to another noid (especially if you are a virgin level of THC consumption): I almost got a voucher for emergencies after 2 small slats! Dizziness not possible (spider position in bed with attempts to take deep breaths to land as quickly as possible…), the impression that the brain is going to burn out, etc. And this even with the 10mg/ml concentration of 5F AKB 48: that is to say... Good ok: we get better quickly but still. »

How to reduce the risks

The description of the contents on the packaging may have nothing to do with the actual contents;

The potency of cannabinoids and different preparations vary widely: start with a very low dose (the size of a match head) and increase doses carefully, giving yourself time for previous doses to wear off;

Find out about the products, effects, doses and routes of administration before taking anything;

Avoid using if you have poor cannabis tolerance

Be very careful about using cannabinoids in bongs or water pipes: it's harder to regulate the intake and easy to take too much;

Dosage the product with a precise method, avoid any dosage "by eye";

Do not use in combination with other drugs, especially other forms of cannabis, alcohol or stimulants;

Synthetic cannabinoids can exacerbate anxiety and paranoia, so use them only in an environment where you feel safe, with people you trust.

In the event of a panic attack or anxiety attack, sit upside down, breathe regularly and practice reassurance. However, if he has more serious symptoms, such as delusional behavior or respiratory distress, he may need medical assistance;

If you experience a prolonged period of rapid heartbeat, or if you experience chest pain call an ambulance;

Do not drive after consuming.

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